HRIG Administration Guidance

The Centers for Disease Control and Prevention (CDC) and the Advisory Committee on Immunization Practices (ACIP) provide guidance on the safe use of vaccines and related biological products, including post-exposure prophylaxis (PEP) for potential rabies exposures. When administered according to ACIP guidelines, including thoroughly infiltrating all wounds with human rabies immune globulin (HRIG), PEP is essentially 100% effective in preventing human rabies.1

The following support tools provide specific guidance on how to properly administer KEDRAB® (Rabies Immune Globulin [Human]):

KEDRAB Administration Guide

A downloadable pdf that outlines the 3 steps of PEP, according to the CDC and ACIP, and provides step-by-step visual guidance on how to properly administer KEDRAB.

KEDRAB Administration Video

This easy-to-follow animation visualizes detailed instructions on how to properly administer KEDRAB to previously unvaccinated patients.

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Learn more about KEDRAB, Rabies, Ordering, Patient Assistance & Product Replacement Programs, and ways to connect with a Sales Representative.

Reference: 1. Centers for Disease Control and Prevention. Human rabies prevention—United States, 2008: recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2008;57(RR-3):1-28.


  • Enhanced color packaging for clear identification of 2mL and 10mL dosage options
  • User-friendly vertical barcodes on vials for easier scanning

New KEDRAB packaging, with distinctive vial sizes and colors, designed to reduce chances of error

Over the next several months, you can expect to start receiving KEDRAB® (Rabies Immune Globulin [Human]) with enhanced product packaging, as pictured above. Products with new packaging will be shipped when available, and after distributors' current supplies become depleted. As such, it is likely you may not receive both the new 2mL and 10mL product packaging at the same time.