Rabies in the United States

About 55,000 People Are Treated With Post-exposure Prophylaxis (PEP) Each Year to Prevent Infection With the Rabies Virus1

  • Canine rabies has been successfully controlled since the 1970s, and wildlife has accounted for more than 90% of all reported animals with rabies since the 1980s2
  • Of over 1 million dogs that enter the United States each year, 10% are from countries where canine rabies virus variant (CRVV) is enzootic, which poses a risk for reintroduction3
  • Vaccination programs (primarily involving raccoons, coyotes, and foxes) have resulted in the reduction of rabies in wildlife, however, vaccinating bats isn’t feasible2
  • Therefore, prevention of human infection with the rabies virus relies on secondary intervention methods such as health education, exposure prevention, and PEP2
Approximately 55,000 people in the United States receive post-exposure prophylaxis each year

92% of Animal Rabies Cases Involved Wildlife Species2

Wildlife species are responsible for most animal rabies cases in the United States



Wildlife species are responsible for most animal rabies cases in the United States



Wildlife species are responsible for most animal rabies cases in the United States



The Global Burden of Rabies

  • The estimated annual global cost of rabies is $8.6 billion4
  • Rabies is present in more than 150 countries and territories worldwide4
  • Someone dies from rabies every 9 minutes5
  • Every year, more than 29 million people receive PEP4
FDA-approval for use in children

Children Are Highly Vulnerable

Globally, 40% of those who are bitten by animals suspected of being infected with the rabies virus are children under the age of 15.4 KEDRAB is the only FDA-approved HRIG studied in children6

References: 1. Centers for Disease Control and Prevention. CDC Vital Signs. Rabies: A Forgotten Killer. June 12, 2019. Accessed February 24, 2021. 2. Ma X, Monroe BP, Cleaton JM, et al. Rabies surveillance in the United States during 2017. J Am Vet Med Assoc. 2018;253(12):1555-1568. doi:10.2460/javma.253.12.1555. 3. Pieracci EG, Pearson CM, Wallace RM, et al. Vital Signs: Trends in Human Rabies Deaths and Exposures — United States, 1938–2018. MMWR Morb Mortal Wkly Rep. 2019;68:524–528. doi:10.15585/mmwr.mm6823e1. 4. World Health Organization. Rabies. Updated April 2020. Accessed October 19, 2020. 5. World Health Organization. Education is vital to prevent rabies deaths. September 26, 2018. Accessed October 19, 2020. 6. KEDRAB [package insert]. Fort Lee, NJ: Kedrion Biopharma Inc.; 2021.