HRIG ADMINISTRATION VIDEO

The Centers for Disease Control and Prevention (CDC) and the Advisory Committee on Immunization Practices (ACIP) provide guidance on the safe use of vaccines and related biological products, including post-exposure prophylaxis (PEP). When administered according to ACIP guidelines, including thoroughly infiltrating all wounds with human rabies immune globulin (HRIG), PEP is essentially 100% effective in preventing human rabies.1

The following video shows an actual patient being administered HRIG in the emergency department as part of PEP after a potential rabies exposure from a fox bite.

  • The healthcare provider properly advises the patient that he needs to administer as much of the dose of human rabies immune globulin as possible into and around the area of the exposure1
  • It is critical to adequately infiltrate all bite wounds and scratches with human rabies immune globulin because every break in the skin is an opportunity for rabies virus to enter the body1

Volume Matters

Ready-to-use KEDRAB ensures you have the appropriate volume needed to treat any rabies exposure. In vulnerable patients, such as children, KEDRAB provides more volume to ensure complete coverage and to help avoid post-exposure prophylaxis failure.2-4

References: 1. Centers for Disease Control and Prevention. Human rabies prevention—United States, 2008: recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2008;57(RR-3):1-28. 2. KEDRAB [package insert]. Fort Lee, NJ: Kedrion Biopharma Inc.; 2021. 3. Wilde H. Failures of post-exposure rabies prophylaxis. Vaccine. 2007;25(4):7605-7609. 4. Wilde H, Sirikawin S, Sabcharoen A, et al. Failure of postexposure treatment of rabies in children. Clin Infect Dis. 1996;22(2):228-232.