The Centers for Disease Control and Prevention (CDC) and the Advisory Committee on Immunization Practices (ACIP) provide guidance on the safe use of vaccines and related biological products, including post-exposure prophylaxis (PEP). When administered according to ACIP guidelines, including thoroughly infiltrating all wounds with human rabies immune globulin (HRIG), PEP is essentially 100% effective in preventing human rabies.1


The Following Videos Provide Specific Guidance on How to Properly Administer KEDRAB® (Rabies Immune Globulin [Human]):

KEDRAB Administration Video

This animated video provides step-by-step visual guidance on how to properly dose and administer KEDRAB to previously unvaccinated patients – for immediate protection from the rabies virus. It also includes details on the 3 crucial steps of PEP (according to the CDC–ACIP), common reasons for PEP failure, and the importance of proper HRIG volume during administration.

Real-World HRIG Administration Video

View an actual patient being administered HRIG in the emergency department as part of PEP after a potential rabies exposure from a fox bite. The healthcare provider properly advises the patient that he needs to administer as much of the HRIG dose as possible into and around the area of the exposure.

HRIG Volume Matters

Ready-to-use KEDRAB ensures you have the appropriate HRIG volume needed to treat any rabies exposure. In vulnerable patients, such as children, KEDRAB provides adequate volume to help ensure complete coverage and to help avoid post-exposure prophylaxis failure.2,3

References: 1. Centers for Disease Control and Prevention. Human rabies prevention—United States, 2008: recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2008;57(RR-3):1-28. 2. KEDRAB [package insert]. Fort Lee, NJ: Kedrion Biopharma Inc.; 2021. 3.  Bookstaver PB, Akpunonu P, Nguyen HB, Swan JT, Howington GT. Administration of rabies immunoglobulin: Improving evidence-based guidance for wound infiltration. Pharmacotherapy. 2021;41(8):644-648.


  • Enhanced color packaging for clear identification of 2mL and 10mL dosage options
  • User-friendly vertical barcodes on vials for easier scanning

New KEDRAB packaging, with distinctive vial sizes and colors, designed to reduce chances of error

Over the next several months, you can expect to start receiving KEDRAB® (Rabies Immune Globulin [Human]) with enhanced product packaging, as pictured above. Products with new packaging will be shipped when available, and after distributors' current supplies become depleted. As such, it is likely you may not receive both the new 2mL and 10mL product packaging at the same time.