KEDRAB Is Supplied in Two Distinctively Different Vial Volumes and Sizes

2-mL vial

2-mL vial

The 2-mL vial contains a total of 300 IU, which is sufficient for a child weighing 15 kg (33 lb)1
NDC 76125-150-02


10-mL vial

The 10-mL vial contains a total of 1500 IU, which is sufficient for an adult weighing 75 kg (165 lb)1
NDC 76125-150-10


Post-exposure prophylaxis consists of a single 20 IU/kg body weight dose of KEDRAB® (Rabies Immune Globulin [Human]) and a full course of rabies vaccine.1

  • Administer KEDRAB as soon as possible after exposure, preferably at the time of the first rabies vaccine dose. However, should a delay occur, administer KEDRAB at any time up to and including seven days after the first dose of rabies vaccine. If there is a delay, initiate post-exposure prophylaxis at any time after exposure.1
  • Do not exceed the recommended dose of KEDRAB because this can partially suppress active production of rabies virus antibodies. Do not administer additional doses of KEDRAB, even if the antibody response to vaccination is delayed.1


KEDRAB is for wound infiltration and intramuscular use.1 

Known Bite Size

  • Infiltrate as much of the dose as possible into and around any detectable bite wounds
  • Administer any remaining KEDRAB intramuscularly into anatomical site(s) distant from the site of the rabies vaccine.

Unknown Bite Size

  • Administer the full KEDRAB dose by the intramuscular route at a site distant from the site of the rabies vaccination



Please see full Prescribing Information here for full dosage and administration information.

Additional administration instructions1: 

  • If a large intramuscular volume is required (>2 mL for children or >5 mL for adults), administer the total volume in divided doses at different sites.
  • Do not mix KEDRAB with the rabies vaccine or administer in the same syringe with the rabies vaccine.
  • Discard unused portion of the product in the vial.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration. If either of these conditions exists, DO NOT use the vial of KEDRAB; call Kedrion Biopharma Inc. Customer Service (1-855-353-7466). Do not discard the vial.1


Is the Volume of your HRIG Dose Adequate for Treating Different Types of Rabies Exposures?

Reference: 1. KEDRAB [package insert]. Fort Lee, NJ: Kedrion Biopharma Inc.; 2021.