The virus has a capacity to kill 99.9% of the people who become infected, making it one of the deadliest diseases in the world.2,3
Once rabies enters the central nervous system, it is almost 100% fatal4
The Five Clinical Stages of Rabies4*
|Incubation||Prodrome||Acute Neurological Phase||Coma||Death|
|Duration||5 days to >2 years||0 – 10 days||2 – 7 days||5 – 14 days||Variable|
Pain or paresthesias at bite site
Lack of coordination
CNS signs (paresis, paralysis)
|Pituitary dysfunction |
*Adapted from CDC Advisory Committee on Immunization Practices 2010.4
Get detailed information about the rabies virus, current post-exposure prophylaxis guidelines, and the efficacy and safety of KEDRAB for rabies exposure.
References: 1. Centers for Disease Control and Prevention. CDC Vital Signs. Rabies: A Forgotten Killer. June 12, 2019. https://www.cdc.gov/vitalsigns/rabies/. Accessed February 24, 2021. 2. Rupprecht C, Kuzmin I, Meslin F. Lyssaviruses and rabies: current conundrums, concerns, contradictions and controversies. F1000Research. 2017;6(F1000 Faculty Rev):184. doi: 10.12688/f1000research.10416.1. 3. Fooks AR, Banyard AC, Horton DL, Johnson N, McElhinney LM, Jackson AC. Current status of rabies and prospects for elimination. Lancet. 2014;384:1389-1399. 4. Centers for Disease Control and Prevention. Use of a reduced (4-dose) vaccine schedule for postexposure prophylaxis to prevent human rabies: recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2010;59(2):1-9. 5. Data on file. Kamada Ltd. 6. Consales CA, Bolzan VL. Rabies review: Immunopathology, clinical aspects and treatment. J Venom Anim Toxins Trop Dis. 2007;13(1); 5-38. 7. KEDRAB [package insert]. Fort Lee, NJ: Kedrion Biopharma Inc.; 2021.