Pediatric HRIG Data Compendium
When it comes to potential rabies exposures, children are more likely to suffer large and complex wounds than adults.1
Administering HRIG in children who have larger, more severe wounds can be challenging. See what the data shows about providing the optimal treatment for pediatric patients in your hospital with potential rabies exposures.
The KEDRAB pediatric HRIG data compendium contains crucial research on:
- Complexities of treating pediatric wounds compared to adults
- Low-volume HRIG challenges when treating pediatric wounds
- Proper infiltration of HRIG to completely neutralize the rabies virus
- Landmark safety and effectiveness study of HRIG in children
- Standard of care for rabies post-exposure prophylaxis (PEP)
- Most common animal exposures leading to rabies PEP
- Confirmation that higher-volume HRIG does not increase chances of compartment syndrome2,3
References: 1. Burke RV, Russo P, Sicilia M, et al. Epidemiology of rabies immune globulin use in paediatric and adult patients in the USA: a cross-sectional prevalence study. BMJ Open. 2022;12(4):e055411. doi:10.1136/bmjopen-2021-055411 2. Shantavasinkul P, Wilde H. Postexposure prophylaxis for rabies in resource-limited/poor countries. Adv Virus Res. 2011;79:291-307. doi:10.1016/B978-0-12-387040-7.00013-5 3. Suwansrinon K, Jaijaroensup W, Wilde H, Sitprija V. Is injecting a finger with rabies immunoglobulin dangerous? Am J Trop Med Hyg. 2006;75(2):363-364.